That is essential, because the method a protein in the human body folds figures out if a pharmaceutical will have the ability to bind to that protein and work. Simply put, we have to understand how these proteins fold if we desire a drug to work. Historically, this has been a trial-and-error procedure (last year). Today, Alpha, Fold can forecast protein folding with 92. 4% precision. That's going to make it much simpler to produce drugs that do what they're developed to do. This was an advancement nearly nobody discovered. But it's going to have extensive ramifications for treating disease. I predict that Alpha, Fold will be 98% accurate by the end of 2021.
And, naturally, there will be a lot of investment opportunities in this space, too. Moving topics It's going to be an excellent year for bitcoin. I'm bullish on it in 2021 (artificial intelligence). That stated, I still think bitcoin will continue to be volatile. We're close to all-time highs. I would not be amazed if it drew back perhaps substantially prior to going higher - diplomatic relations. I have actually been covering bitcoin for a very long time now. Among the first research reports I ever published was on bitcoin. That remained in June 2015. At the time, bitcoin was trading for about $240. Bitcoin trades for over $34,000 today.
However at the time of that preliminary recommendation, I entitled my report "What's the Big Offer With Bitcoin?" That shows you where the conversation was at the time. We were mainly educating readers. But that's not the huge concern any longer. Now we're seeing institutional money lastly take an interest in bitcoin. Massachusetts Mutual Life Insurance coverage took a $100 million stake in bitcoin in December. This is not some small, niche enterprise. Mass, Mutual is a relied on 170-year-old institution. So consider that. In 5 years, we went from informing readers on what bitcoin is to a company like Mass, Mutual taking a $100 million stake.
And that's a huge factor I'm bullish on it this year. jeff brown biotech genome sequencing. Regards, Jeff Brown, Editor, The Bleeding Edge I have a benefit prediction 2020 was a record year for IPOs. 552 U.S. business went public the most in more than twenty years. These business raised a total of $172 billion. That's an all-time high beating the previous annual record by 43%. I anticipate 2021 will be another record year in IPOs. There are many excellent personal business on the brink of striking the general public markets And I've been dealing with a new way for you to invest even before these companies go public.
This chance has actually been building over the last few years. I can't wait to tell you all about it. Join me tomorrow at 8 p. m. ET for my Pre-IPO Code Event to discover all the details. Go right here to schedule your area totally free.
Emma Walsh here, handling editor of the Journal. Regular Journal readers understand that tech isn't our usual beat (biotech stock). And when it comes to tech investing, we leave it to the experts. Thankfully, we have a number of such professionals in our Rolodex. Our associate Jeff Brown will recognize to our longtime readers. He is one of the most accomplished tech investing professionals we understand (white house). In truth, he had numerous triple-digit returns in his Brownstone Research study portfolios in 2015. Here's what Jeff believes the tech sector will bring us in 2021 Each year, I like to have a look at the huge image and anticipate what's simply around the corner.
That includes things like 5G networks, biotech, expert system, and far more. These trends are experiencing exponential growth and developing unbelievable chances for investors. I want to make sure all our readers are prepared for what's next. And with that in mind, let me draw the photo of what I see coming in the next 12 months Our brand-new 5G (fifth-generation) wireless networks are a topic I have actually been covering for years now. second wave. But in spite of what numerous readers might think, this is a trend that's just beginning. Although the COVID-19 pandemic interfered with supply chains last year, an excellent 250 million 5G-enabled devices were still sold.
And all of this ultimately caused Apple postponing the release of the 5G-enabled i, Phone 12 by two months (jeff brown prediction for 2021). Losing 2 months of manufacturing and sales really impacts the number of 5G gadgets are sold in the calendar year. When you think about all of that, offering 250 million units is remarkable. More importantly, the hold-ups brought on by the pandemic created a lots of bottled-up demand. And that demand is now going to be pushed into 2021. In reality, I predict that more than 500 million 5G gadgets will be shipped in 2021 - bleeding edge. Which's not my only 5G prediction When I've talked about 5G in the past, I've explained its three different stages.
In Stage Two, 5G devices go on sale. 5G phones and other items start to reach customers. And in Phase 3, 5G services begin to be offered (jeff brown latest prediction). That's when we start to see applications running on 5G networks. Think about things like massive multiplayer video games over a smart phone. That's not possible with 4G. It will be with 5G. And my second 5G prediction for 2021 is that we will start Stage Three by this summer. This begins something of a virtuous cycle: Most individuals don't truly care about the technology. But they will care if there are interesting applications that can only be accessed with a 5G phone.
That causes more 5G apps being developed. In reality, 5G is going to open up a suite of extraordinary applications: self-driving cars and trucks, the Web of Things, robotic surgery, and more. All of these technologies require 5G. The financial investment chances moving forward will be enormous. Stepping away from 5G, the next essential technology I visualize in 2021 is CRISPR genetic modifying. CRISPR means "clustered regularly interspaced brief palindromic repeat." It's a mouthful. But it's one of the most amazing advancements in biotechnology. At a high level, CRISPR is a technology that can edit our hereditary makeup as if it were software.
The program can crash or not work properly. CRISPR uses a comparable idea however with our genetic code. "Typos" in our genome can lead to illness. CRISPR can remedy these "typos." For years, CRISPR was mainly a niche innovation that wasn't well understood. And throughout that time, there were really just three companies operating in this space. However things are altering. CRISPR is no longer just theoretical. We're seeing actual results. We're treating illness and seeing that this innovation simply works. And as a result, a "second crop" of early-stage CRISPR companies is going public and providing unbelievable returns. This whole market is effectively a greenfield opportunity.
There's room for many companies to exist in this area. diplomatic relations. And there will be more. That's my forecast for CRISPR in 2021. I forecast that 2 or three more hereditary editing business will hold their IPOs. Sticking with biotechnology, we are seeing remarkable things occurring at the merging of biotech and artificial intelligence (AI). Google's AI subsidiary, Deep, Mind, simply announced at the end of 2020 that its most current Alpha, Fold software application can properly forecast the folding of a protein based exclusively on its amino acid series with 92. 4% accuracy. That is necessary because the way a protein in the human body folds figures out if a pharmaceutical will have the ability to bind to that protein and be efficient.
Historically, this has been an experimental procedure. Today, Alpha, Fold can predict protein folding with 92. 4% precision. That's going to make it a lot easier to create drugs that do what they're created to do. And here's my next prediction. I forecast that Alpha, Fold will be 98% precise by the end of 2021. And we will see not just one but numerous drug therapies produced using this innovation. This was among those advancements that nearly no one saw. However it's going to have extensive implications for treating illness. And, of course, there will be lots of investment chances in this area, too.
It's going to be an excellent year for bitcoin. I'm bullish on it in 2021. That said, I still believe bitcoin will continue to be unpredictable. We're close to all-time highs. I would not be shocked if it pulled back perhaps significantly before going greater. I have actually been covering bitcoin for a long period of time now. Among the very first research reports I ever published was on bitcoin - future report. That remained in June 2015. At the time, bitcoin was trading for about $240. Bitcoin trades for over $40,000 today. So that's a 16,500%+ roi for anybody who followed my recommendation. However at the time of that initial recommendation, I titled my report, "What's the Big Deal With Bitcoin?" That shows you where the discussion was at the time.
However no one is asking that concern anymore. Now, we're seeing institutional cash finally taking an interest in bitcoin. The huge news was that Massachusetts Mutual Life Insurance took a $100 million stake in bitcoin in December. This is not some small, specific niche business. jeff brown predictions 2021. Mass, Mutual is a 150-year-old institution. So consider that. In five years, we went from informing readers on what bitcoin is to a company like Mass, Mutual taking a $100 million stake. The institutional adoption of bitcoin will continue. Which's a big reason that I'm bullish on it this year. Regards, Jeff Brown, Editor, The Bleeding Edge I have another benefit forecast In 2021, we're going to have another record year in IPOs. One site reports that Jeff Brown is worth about $27. 5 million and declares the info is up to date as of February 2021, but we could not separately verify this claim. Given Jeff Brown's past, he likely has a considerable net worth, however we can't hammer down an exact figure at this moment. Brown is best understood for his sage-like capability to select winning technology stocks. He invested more than 25 years looking into innovation companies like Qualcomm, NXP semiconductors, and Juniper Networks. Brown's substantial experience provides him an outstanding perspective on the market. He's constantly on the hunt for brand-new chances, and he shares a number of his finest choices in the Future Report.
That's full marks, but it's not ridiculously reasoned. Brown has an excellent credibility as a stock-picker, and he effectively predicted a few of the biggest financial events of the past twenty years. Although he doesn't appear to release his picks to the public, the service's success is a direct indicator of Brown's stock-picking prowess. No one on Wall Street gets it best every time, but Jeff Brown's accurate predictions have actually earned him legions of devoted fans. That states a lot about his capability. The Future Report is released by Brownstone Research, a popular financial research publisher. Brownstone Research offers several research services with a variety of expertises - white house.
The company is likewise associated with Bonner & Partners, another well-respected research study publisher - jeff brown top biotech stock 2021. On its website, Brownstone states its mission is to provide retail investors with professional-grade research study: "For too long, the finest investment research has actually not been readily available to specific investors. It has been usually booked for investment banks, hedge funds, personal equity, and high-net-worth customers. tech predictions. The mission of Brownstone Research is to make that kind of proprietary research study offered to any financiers looking to gain an edge in the markets. The objective is basic to deliver distinct and successful investment research study discovered no place else." -Brownstone Research website excerpt from the Jeff Brown is the founder of Brownstone Research study, and he likewise works as the firm's Chief Investment Expert.
With Brown guiding the ship, Brownstone Research is a powerhouse publisher with lots to provide its customers. After decades of constant success at the helm of top-tier companies like Tesla and Area, X, Elon Musk is a household name throughout many of America. If you understand even a bit about the marketplace, you know that he has a reputation as a King Midas of sorts. tech stock. Everything he touches relies on gold! Jeff is well mindful of Elon Musk's executive expertise, so he constantly has an eye out for the Silicon Valley rock star's next relocation. This time, Jeff has an early lead on Elon's next big task.
In truth, Brown believes S.A.V. jeff brown top biotech stock 2021. could be "the most significant pattern of the 2020s, and he's not alone. Check out these quotes from other popular S.A.V. bulls: Elon's next huge act will be weding 2 innovative innovations: synthetic intelligence and electric cars and trucks. Musk hopes the combination will help him establish the very first fully-autonomous, self-driving cars ever. It's absolutely nothing except the vehicle market's Holy Grail. As you know, electric vehicles and self-driving vehicle stocks have been substantial this year, but the Wall Street device has actually been big on buzz without much concrete outcome. Despite an extreme increase in competition over the past couple of years, Brown still believes Musk has the best opportunity of putting everything together.
tech might be the magic string that ties all of it together. S.A.V. represents Shared Autonomous Vehicle, and it might be the future of transportation. Basically, this technology would permit you to rent your car as a self-governing, self-driving taxi when you're not using it. You just leave the car and press a button on an app that tells the vehicle to "sign up with the fleet." Next thing you know, you're relaxing on your sofa while your automobile shuttles ride-sharers around town. Best of all, you get to keep a large piece of the earnings. It sounds insane, but it could be closed than you believe.